MAGI3 - membrane associated guanylate kinase, WW and PDZ domain containing 3 Gene

Homo sapiens

Also known as MAGI-3; dJ730K3.2

Gene ID: 260425 | Gene type: protein coding

About MAGI3

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:113,390,515-113,685,923 (from NCBI)

This gene has 6 transcripts (splice variants), 295 orthologues and 6 paralogues. Broad expression in lung (RPKM 6.5), thyroid (RPKM 5.4) and 24 other tissues.

Summary

Predicted to enable Frizzled binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of JUN kinase activity. Located in cell junction. [provided by Alliance of Genome Resources, Apr 2022]

MAGI3 Products(2)

mRNA	Protein	Name
NM_001142782.2	NP_001136254.1	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform 1
NM_152900.3	NP_690864.2	membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform 2

MAGI3 Protein Structure

Guanylate_kin

PDZ

0
300
600
900
1200
1481 a.a.

Protein Preferred Names

Protein Names

membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

membrane-associated guanylate kinase inverted 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07983	MAGI3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MAGI3	VGNC	VGNC:74400
Mus musculus	MAGI3	MGD	MGI:1923484
Bos taurus	MAGI3	VGNC	VGNC:31148
Felis catus	MAGI3	VGNC	VGNC:63366
Canis familiaris	MAGI3	VGNC	VGNC:42929
Rattus norvegicus	MAGI3	RGD	RGD:621362

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