2. Gene
  3. RGS22 - regulator of G protein signaling 22 Gene

RGS22 - regulator of G protein signaling 22 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CT145; PRTD-NY2

Gene ID: 26166 | Gene type: protein coding

About RGS22

Cytogenetic location: 8q22.2 Genomic coordinates (GRCh38): 8:99,960,936-100,106,049 (from NCBI)

This gene has 17 transcripts (splice variants), 189 orthologues and 23 paralogues. Biased expression in testis (RPKM 35.2), ovary (RPKM 3.9) and 1 other tissue.

Summary

Enables G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Located in actin cytoskeleton; cytosol; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

RGS22 Products(3)

mRNA Protein Name
NM_001286692.2 NP_001273621.1 regulator of G-protein signaling 22 isoform 2
NM_001286693.2 NP_001273622.1 regulator of G-protein signaling 22 isoform 3
NM_015668.5 NP_056483.3 regulator of G-protein signaling 22 isoform 1

RGS22 Protein Structure

RGS

RGS: Regulator of G protein signaling domain (676 - 771)

RGS

RGS: Regulator of G protein signaling domain (853 - 977)

RGS

RGS: Regulator of G protein signaling domain (1022 - 1134)

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  • 1264 a.a.
Protein Preferred Names Protein Names

regulator of G-protein signaling 22

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11918 RGS22 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RGS22 VGNC VGNC:45532
Rattus norvegicus RGS22 RGD RGD:1565493
Macaca mulatta RGS22 VGNC VGNC:82221
Mus musculus RGS22 MGD MGI:3613651
Felis catus RGS22 VGNC VGNC:81693
Bos taurus RGS22 VGNC VGNC:33921