country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

ARSF - arylsulfatase F Gene

Also Known as ASF

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 416

About ARSF

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:3,040,234-3,112,727 (from NCBI)

This gene has 2 transcripts (splice variants), 307 orthologues and 16 paralogues. Biased expression in kidney (RPKM 3.3), skin (RPKM 2.1) and 5 other tissues.

Summary

This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011]

ARSF Products (3)

mRNA	Protein	Name
NM_001201538.2	NP_001188467.1	arylsulfatase F precursor
NM_001201539.2	NP_001188468.1	arylsulfatase F precursor
NM_004042.5	NP_004033.2	arylsulfatase F precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables arylsulfatase activity	IDA IDA: Inferred from direct assay	9192838	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARSF Protein Structure

Sulfatase

Sulfatase_C

0
100
200
300
400
500
590 a.a.

Protein Preferred Names	Protein Names
arylsulfatase F

Related Diseases

Diseases	Alias
Martin-Probst Syndrome	Deafness-Intellectual Disability, Martin-Probst Type Syndrome Martin-Probst Deafness-Mental Retardation Syndrome Mental Retardation, X-Linked, Syndromic, Martin-Probst Type MRXSMP Deafness-Intellectual Disability Syndrome, Martin-Probst Type Hearing Loss-Intellectual Disability Syndrome, Martin-Probst Type X-Linked Deafness-Intellectual Disability Syndrome Syndrome X-Linked Hearing Loss-Intellectual Disability Syndrome Syndrome
Gastric Dilatation	Stomach Dilatation
Hypertrophic Pyloric Stenosis	Congenital Hypertrophic Pyloric Stenosis Pyloric Stenosis, Hypertrophic Congenital Or Infantile Stricture Of Pylorus Achalasia Of The Pylorus Congenital Hypertrophy Of The Pylorus Infantile Hypertrophy Of The Pylorus Infantile Constriction Of The Pylorus Congenital Stenosis Of The Pylorus Congenital Constriction Of The Pylorus Congenital Stricture Of The Pylorus Infantile Hypertrophic Pyloric Stenosis Infantile Stenosis Of The Pylorus Infantile Stricture Of The Pylorus Congenital Or Infantile Constriction Of Pylorus Infantile Pyloric Obstruction Infantile Pyloric Hypertrophy Pylorus Achalasia Pyloric Constriction Infantile Pyloric Stricture Infantile Pyloric Stenosis Congenital Spasm Of Pylorus Congenital Pylorospasm Congenital Pyloric Stricture Congenital Pyloric Spasm Congenital Or Infantile Spasm Of Pylorus Congenital Or Infantile Obstruction Of Pylorus Congenital Pyloric Stenosis
Opitz-Kaveggia Syndrome	Fg Syndrome Fgs1 Fgs Keller Syndrome OKS Fg Syndrome 1 Fg Syndrome Type 1 Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, And Partial Agenesis Of Corpus Callosum Intellectual Disability, Large Head, Imperforate Anus, Congenital Hypotonia, And Partial Agenesis Of Corpus Callosum Mental Retardation, Large Head, Imperforate Anus, Congenital Hypotonia, And Partial Agenesis Of The Corpus Callosum

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01037	ARSF Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown