BCL2L15 - BCL2 like 15 Gene

Also Known as Bfk; C1orf178

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 440603

About BCL2L15

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:113,876,816-113,887,581 (from NCBI)

This gene has 7 transcripts (splice variants) and 106 orthologues. Biased expression in duodenum (RPKM 22.4), small intestine (RPKM 18.2) and 5 other tissues.

Summary

Predicted to be involved in apoptotic process and regulation of apoptotic process. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

BCL2L15 Products (1)

mRNA Protein Name
NM_001010922.3 NP_001010922.1 bcl-2-like protein 15

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bcl-2-like protein 15

  • bcl-2 family kin

BCL2L15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
BCL2L15 Q5TBC7 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
BCL2L15 Q5TBC7 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
BCL2L15 Q5TBC7 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
BCL2L15 Q5TBC7 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
BCL2L15 Q5TBC7 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra
BCL2L15 Q5TBC7 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra
BCL2L15 Q5TBC7 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra
BCL2L15 Q5TBC7 POLR2G Homo sapiens P62487
Y2H Prey Pooling
32296183
Intra
BCL2L15 Q5TBC7 POLR2G Homo sapiens P62487
Y2H Array
32296183
Intra
BCL2L15 Q5TBC7 TEAD2 Homo sapiens Q15562
Validated Y2H
25416956
Intra
BCL2L15 Q5TBC7 TEAD2 Homo sapiens Q15562
Y2H Prey Pooling
25416956
Intra
BCL2L15 Q5TBC7 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra
BCL2L15 Q5TBC7 PAX6 Homo sapiens P26367
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-149625 Bcl-2-IN-15 Inhibitor / Unkown
HY-RS01433 BCL2L15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus BCL2L15 VGNC VGNC:26449
Canis familiaris BCL2L15 VGNC VGNC:38411
Rattus norvegicus BCL2L15 RGD RGD:1562344
Felis catus BCL2L15 VGNC VGNC:60086
Macaca mulatta BCL2L15 VGNC VGNC:70162
Mus musculus BCL2L15 MGD MGI:2685412
Others BCL2L15 NCBI