SMU1 - SMU1 DNA replication regulator and spliceosomal factor Gene

Homo sapiens

Also known as BWD; SMU-1; fSAP57

Gene ID: 55234 | Gene type: protein coding

About SMU1

Cytogenetic location: 9p21.1 Genomic coordinates (GRCh38): 9:33,041,765-33,076,674 (from NCBI)

This gene has 1 transcript (splice variant) and 212 orthologues. Ubiquitous expression in brain (RPKM 7.9), thyroid (RPKM 7.2) and 25 other tissues.

Summary

Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

SMU1 Products(1)

mRNA	Protein	Name
NM_018225.3	NP_060695.2	WD40 repeat-containing protein SMU1

SMU1 Protein Structure

WD40

0
100
200
300
400
513 a.a.

Protein Preferred Names

Protein Names

WD40 repeat-containing protein SMU1

DNA replication regulator and spliceosomal factor

Related Diseases

Diseases

Alias

Influenza

Flu	Influenza With Non-Respiratory Manifestation
Influenza With Other Manifestations	Influenza, Human
Influenza, Susceptibility To	Seasonal Influenza, Virus Identified

Mandibular Cancer

Mandibular Neoplasms	Malignant Neoplasm Of Inferior Maxilla
Malignant Neoplasm Of Lower Jaw Bone	Malignant Neoplasm Of Mandible
Mandible Cancer	Mandibular Neoplasm
Neoplasm Of Mandible

Exudative Vitreoretinopathy 2, X-Linked

EVR2	Evrx
Fevrx	X-Linked Exudative Vitreoretinopathy 2
Exudative Vitreoretinopathy, Familial, 2	Fevr, X-Linked
Vitreoretinopathy, Exudative 2	Exudative Vitreoretinopathy Familial 2
Fevr X-Linked	X-Linked Familial Exudative Vitreoretinopathy
Vitreoretinopathy, Exudative, X-Linked, Type 2	Exudative Vitreoretinopathy, Familial, X-Linked Recessive

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13457	SMU1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SMU1	RGD	RGD:620694
Macaca mulatta	SMU1	VGNC	VGNC:77733
Bos taurus	SMU1	VGNC	VGNC:35038
Canis familiaris	SMU1	VGNC	VGNC:46578
Felis catus	SMU1	VGNC	VGNC:97637
Mus musculus	SMU1	MGD	MGI:1915546

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