2. Gene
  3. TMEM108 - transmembrane protein 108 Gene

TMEM108 - transmembrane protein 108 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RTLN; CT124

Gene ID: 66000 | Gene type: protein coding

About TMEM108

Cytogenetic location: 3q22.1 Genomic coordinates (GRCh38): 3:133,038,391-133,397,775 (from NCBI)

This gene has 11 transcripts (splice variants) and 181 orthologues. Broad expression in brain (RPKM 3.1), testis (RPKM 2.8) and 19 other tissues.

Summary

Predicted to be involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; nervous system development; and regulation of signal transduction. Predicted to be located in somatodendritic compartment. Predicted to be active in axon; endosome; and postsynaptic density. [provided by Alliance of Genome Resources, Apr 2022]

TMEM108 Products(3)

mRNA Protein Name
NM_001136469.3 NP_001129941.1 transmembrane protein 108 isoform 1 precursor
NM_001282865.2 NP_001269794.1 transmembrane protein 108 isoform 2 precursor
NM_023943.4 NP_076432.1 transmembrane protein 108 isoform 1 precursor
Protein Preferred Names Protein Names

transmembrane protein 108

cancer/testis antigen 124

Related Diseases

Diseases Alias
Alzheimer Disease 18

AD18

Alzheimer'S Disease 18

Alzheimer Disease 18, Late-Onset

Alzheimer Disease 18, Susceptibility To

Alzheimer'S Disease 18, Late Onset

Alzheimer Disease 18 Late-Onset

Alzheimer Disease, Susceptibility To, Type 18
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14649 TMEM108 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMEM108 VGNC VGNC:47449
Mus musculus TMEM108 MGD MGI:1932411
Felis catus TMEM108 VGNC VGNC:66258
Macaca mulatta TMEM108 VGNC VGNC:79714
Bos taurus TMEM108 VGNC VGNC:35948
Rattus norvegicus TMEM108 RGD RGD:1311530