VIL1 - villin 1 Gene

Homo sapiens

Also known as VIL; D2S1471

Gene ID: 7429 | Gene type: protein coding

About VIL1

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,419,123-218,453,295 (from NCBI)

This gene has 5 transcripts (splice variants), 166 orthologues and 7 paralogues. Biased expression in small intestine (RPKM 141.0), duodenum (RPKM 126.6) and 3 other tissues.

Summary

This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border Cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008]

VIL1 Products(1)

mRNA	Protein	Name
NM_007127.3	NP_009058.2	villin-1

VIL1 Protein Structure

Gelsolin

VHP

0
200
400
600
827 a.a.

Protein Preferred Names

Protein Names

villin-1

Related Diseases

Diseases

Alias

Contagious Pustular Dermatitis

Ecthyma, Contagious	Orf
Ecthyma Contagiosum	Scabby Mouth
Sheep Pox	Thistle Disease
Contagious Pustular Dermatosis

Milker'S Nodule

Poxviridae Infections	Milker Nodule
Milkers' Node	Paravaccinia
Pseudocowpox	Milker'S Nodes

Liver Disease

Liver Failure	Liver Diseases
Abnormality Of The Liver	Liver Dysfunction
Disorder Of Liver	Hepatic Disorder
Hepatic Disease	Disease Of Bilirubin Metabolism
Disorder Of Bilirubin Metabolism	Liver Decompensation
Liver Function Failure	Hepatic Failure Nos
Liver Failure Nos	End Stage Liver Disease
Decompensated Liver Failure	Decompensation Of Liver Function
Hepatic Decompensation	Hepatic Insufficiency
Liver Cell Necrosis With Hepatic Failure	Liver Insufficiency
Decompensated Liver Disease	End Stage Liver Failure
Liver Necrosis With Hepatic Failure

Spondyloepiphyseal Dysplasia, Nishimura Type

SEDN	Spondyloepiphyseal Dysplasia Nishimura Type

Meckel Diverticulum

Meckel'S Diverticulum

Persistent Vitelline Duct

Chemical Colitis

Colonic Benign Neoplasm

Colon Neoplasm	Colonic Mass
Colonic Tumor	Neoplasm Of Colon
Neoplasm Of The Colon	Colonic Neoplasms
Colon Cancer	Colon Carcinoma Nos
Colonic Cancer	Metastatic Colon Cancer Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15650	VIL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	VIL1	MGD	MGI:98930
Rattus norvegicus	VIL1	RGD	RGD:1307048
Canis familiaris	VIL1	VGNC	VGNC:48261
Macaca mulatta	VIL1	VGNC	VGNC:78768
Felis catus	VIL1	VGNC	VGNC:66942
Bos taurus	VIL1	VGNC	VGNC:36794

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