2. Gene
  3. VEZF1 - vascular endothelial zinc finger 1 Gene

VEZF1 - vascular endothelial zinc finger 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DB1; ZNF161

Gene ID: 7716 | Gene type: protein coding

About VEZF1

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:57,971,552-57,988,254 (from NCBI)

This gene has 4 transcripts (splice variants), 267 orthologues and 36 paralogues. Ubiquitous expression in thyroid (RPKM 19.6), endometrium (RPKM 18.2) and 25 other tissues.

Summary

Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.[supplied by OMIM, Sep 2008]

VEZF1 Products(2)

mRNA Protein Name
NM_001330393.2 NP_001317322.1 vascular endothelial zinc finger 1 isoform 2
NM_007146.3 NP_009077.2 vascular endothelial zinc finger 1 isoform 1

VEZF1 Protein Structure

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (74 - 93)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (188 - 213)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (218 - 242)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (261 - 283)

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  • 521 a.a.
Protein Preferred Names Protein Names

vascular endothelial zinc finger 1

putative transcription factor DB1

Related Diseases

Diseases Alias
Acute Apical Periodontitis

Acute Apical Periodontitis Of Pulpal Origin

Acute Apical Periodontitis Nos

Aap - [Acute Apical Periodontitis]
Hypertensive Retinopathy
Robinow Syndrome, Autosomal Dominant 2

Autosomal Dominant Robinow Syndrome 2

DRS2

Robinow, Autosomal Dominant Syndrome, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15641 VEZF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris VEZF1 VGNC VGNC:48256
Bos taurus VEZF1 VGNC VGNC:36788
Rattus norvegicus VEZF1 RGD RGD:1308058
Macaca mulatta VEZF1 VGNC VGNC:99331
Mus musculus VEZF1 MGD MGI:1313291
Felis catus VEZF1 VGNC VGNC:99571