TRIM55 - tripartite motif containing 55 Gene

Homo sapiens

Also known as RNF29; muRF2; MURF-2

Gene ID: 84675 | Gene type: protein coding

About TRIM55

Cytogenetic location: 8q13.1 Genomic coordinates (GRCh38): 8:66,113,351-66,175,485 (from NCBI)

This gene has 5 transcripts (splice variants), 272 orthologues and 80 paralogues. Biased expression in heart (RPKM 14.3), liver (RPKM 6.5) and 2 other tissues.

Summary

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, Myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

TRIM55 Products(4)

mRNA	Protein	Name
NM_033058.3	NP_149047.2	tripartite motif-containing protein 55 isoform 2
NM_184085.2	NP_908973.1	tripartite motif-containing protein 55 isoform 1
NM_184086.2	NP_908974.1	tripartite motif-containing protein 55 isoform 3
NM_184087.2	NP_908975.1	tripartite motif-containing protein 55 isoform 4

TRIM55 Protein Structure

zf-C3HC4_2

zf-B_box

0
100
200
300
400
500
548 a.a.

Protein Preferred Names

Protein Names

tripartite motif-containing protein 55

muscle specific ring finger 2

Related Diseases

Diseases

Alias

Hyaline Body Myopathy

Myosin Storage Myopathy	Autosomal Dominant Hyaline Body Myopathy
Myopathy, Myosin Storage

Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy	Cardiomyopathy, Hypertrophic
Cardiomyopathy Hypertrophic Obstructive	Cardiomyopathy, Hypertrophic, Familial
Idiopathic Myocardial Hypertrophy	Idiopathic Hypertrophic Cardiomyopathy
Obstructive Idiopathic Hypertrophic Cardiomyopathy	Obstructive Cardiomyopathy
Idiopathic Hypertrophic Subaortic Stenosis	Muscular Subaortic Stenosis
Hypertrophic Obstructive Subaortic Stenosis

Noonan Syndrome 8

NS8	Noonan Syndrome, Type 8

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15056	TRIM55 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TRIM55	VGNC	VGNC:78951
Rattus norvegicus	TRIM55	RGD	RGD:1306943
Bos taurus	TRIM55	VGNC	VGNC:36341
Mus musculus	TRIM55	MGD	MGI:3036269
Felis catus	TRIM55	VGNC	VGNC:66545
Canis familiaris	TRIM55	VGNC	VGNC:47827

Name
Email *

	Sorry, but the email address you supplied was invalid.