1. Gene
  2. RCE1 - Ras converting CAAX endopeptidase 1 Gene

RCE1 - Ras converting CAAX endopeptidase 1 Gene

Homo sapiens

Also known as FACE2; RCE1A; RCE1B

Gene ID: 9986 | Gene type: protein coding

About RCE1

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:66,843,441-66,846,552 (from NCBI)

This gene has 9 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in bone marrow (RPKM 9.2), placenta (RPKM 8.3) and 25 other tissues.

Summary

This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This Enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008]

RCE1 Products(2)

mRNA Protein Name
NM_001032279.2 NP_001027450.1 CAAX prenyl protease 2 isoform 2
NM_005133.3 NP_005124.1 CAAX prenyl protease 2 isoform 1

RCE1 Protein Structure

Abi

Abi: CAAX protease self-immunity (164 - 267)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

CAAX prenyl protease 2

RCE1 homolog, prenyl protein peptidase

Related Diseases

Diseases Alias
Atrial Septal Defect 1

ASD1

Atrial Heart Septal Defect 1

Asd

Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

ADLD

Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy

Leukodystrophy, Adult-Onset, Autosomal Dominant

Adult-Onset Autosomal Dominant Leukodystrophy

Autosomal Dominant Leukodystrophy With Autonomic Disease

Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy

Multiple Sclerosis-Like Disorder

Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly

Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease

Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type

Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms

Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy

Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset

Pelizaeus-Merzbacher Disease Autosomal Dominant

Pelizaeus-Merzbacher Disease Late-Onset Type

Adult Onset Autosomal Dominant Leukodystrophy

Emery-Dreifuss Muscular Dystrophy 2, Autosomal Dominant

EDMD2

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy

Emd2

Emery-Dreifuss Muscular Dystrophy, Autosomal Dominant

Scapuloilioperoneal Atrophy With Cardiopathy

Muscular Dystrophy With Early Contractures And Cardiomyopathy, Autosomal Dominant

Hauptmann-Thannhauser Muscular Dystrophy

Cardiomyopathy, Dilated, With Quadriceps Myopathy

Autosomal Dominant Emery-Dreifuss Muscular Dystrophy 2

Muscular Dystrophy, Limb-Girdle, Type 1b

Muscular Dystrophy, Limb-Girdle, Type 1b, Formerly

Lgmd1b, Formerly

Muscular Dystrophy, Proximal, Type 1b, Formerly

Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1b

Lgmd1b

Limb-Girdle Muscular Dystrophy 1b

Muscular Dystrophy, Proximal, Type 1b

Muscular Dystrophy With Early Contractures And Cardiomyopathy Autosomal Dominant

Cardiomyopathy, Dilated, 1a

Dilated Cardiomyopathy 1a

Cdcd1

CMD1A

Cardiomyopathy, Familial Idiopathic

Familial Dilated Cardiomyopathy With Conduction Defect Due To Lmna Mutation

Cardiomyopathy, Dilated, With Conduction Defect 1

Cardiomyopathy, Idiopathic Dilated

Cardiomyopathy, Congestive

Dilated Cardiomyopathy With Conduction Defect 1

Cardiomyopathy Dilated With Conduction Defect Type 1

Cardiomyopathy, Dilated 1a

Cardiomyopathy Dilated With Conduction Defect 1

Cardiomyopathy, Dilated, Type 1a

Hutchinson-Gilford Progeria Syndrome

Progeria

HGPS

Hutchinson-Gilford Syndrome

Hutchinson-Gilford Progeria

Hutchinson Gilford Syndrome

Hutchinson Gilford Progeria Syndrome

Hutchinson-Gilford Disease

Progeria Of Childhood

Hutchinson-Gilford-Progeria Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus RCE1 VGNC VGNC:33828
Macaca mulatta RCE1 VGNC VGNC:76727
Mus musculus RCE1 MGD MGI:1336895
Rattus norvegicus RCE1 RGD RGD:1309261
Felis catus RCE1 VGNC VGNC:64548
Canis familiaris RCE1 VGNC VGNC:56093