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  4. Glyco-diosgenin

Glyco-diosgenin 

Cat. No.: HY-137179 Purity: 98.03%
COA Handling Instructions

Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins.

For research use only. We do not sell to patients.

Glyco-diosgenin Chemical Structure

Glyco-diosgenin Chemical Structure

CAS No. : 1402423-29-3

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 121 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 121 In-stock
Solid
5 mg USD 70 In-stock
10 mg USD 110 In-stock
25 mg USD 220 In-stock
50 mg USD 350 In-stock
100 mg USD 560 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Glyco-diosgenin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Glyco-diosgenin is a synthetic surfactant and detergent for extracting proteins from membranes for structure and function studies, and single-particle cryo-electron microscopy (cryoEM) studies of membrane proteins[1][2].

In Vitro

Glyco-diosgenin (16 h) solubilizes and purifies the twin-arginine translocation BC (TatBC) complex[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Glyco-diosgenin Related Antibodies
Molecular Weight

1165.31

Appearance

Solid

Formula

C56H92O25
CAS No.
SMILES

C[C@@]([C@@]1([H])C2)(CC[C@@]3([H])[C@@]1([H])CC=C(C4)[C@@]3(CC[C@@H]4OCCC(CO[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O[C@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)CO)CO[C@@H]([C@@H]([C@H]7O)O)O[C@@H]([C@H]7O[C@H]([C@@H]([C@H]8O)O)O[C@@H]([C@H]8O)CO)CO)C)[C@]9([H])[C@@]2([H])O[C@@](CC[C@H]%10C)(OC%10)[C@H]9C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (85.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8581 mL 4.2907 mL 8.5814 mL
5 mM 0.1716 mL 0.8581 mL 1.7163 mL
10 mM 0.0858 mL 0.4291 mL 0.8581 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (1.78 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (1.78 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (1.78 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 98.03%

COA (258 KB) HNMR (347 KB) LCMS (260 KB)

Handling Instructions (2659 KB)
References
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Glyco-diosgenin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Glyco-diosgenin1402423-29-3Biochemical Assay Reagentssurfactantdetergentmembranessingle-particlecryo-electronmicroscopycryoEMInhibitorinhibitorinhibit

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