2. Academic Validation
  3. Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

  • Molecules. 2019 Apr 8;24(7):1371. doi: 10.3390/molecules24071371.
Sio-Hong Lam 1,  Yue-Chiun Li 2,  Ping-Chung Kuo 3,  Tsong-Long Hwang 4 5 6,  Mei-Lin Yang 7,  Chien-Chiao Wang 8,  Jason T C Tzen 9
Affiliations

Affiliations

  • 1 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 2 Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. [email protected].
  • 3 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 4 Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. [email protected].
  • 5 Research Center for Industry of Human Ecology, Research Center for Chinese Herbal Medicine, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan. [email protected].
  • 6 Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. [email protected].
  • 7 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. [email protected].
  • 8 Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. [email protected].
  • 9 Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. [email protected].
PMID: 30965630 DOI: 10.3390/molecules24071371
Abstract

Seventy-three compounds were identified from the methanol extract of V. luteola, and among these, three new (1⁻3) were characterized by spectroscopic and mass spectrometric analyses. The isolated constituents were assessed for anti-inflammatory potential evaluation, and several purified principles exhibited significant superoxide anion and Elastase inhibitory effects.

Keywords

elastase release; fabaceae; sesquiterpenoid; superoxide anion generation.

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