1. Epigenetics
  2. Histone Methyltransferase
  3. AMG-193

AMG-193 (compound 481) is an inhibitor of PRMT5. PRMT5-IN-27 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM.

For research use only. We do not sell to patients.

AMG-193 Chemical Structure

AMG-193 Chemical Structure

CAS No. : 2790567-82-5

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Description

AMG-193 (compound 481) is an inhibitor of PRMT5. PRMT5-IN-27 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].

Molecular Weight

444.41

Formula

C22H19F3N4O3

CAS No.
SMILES

O=C(N1[C@@H](C2=CC=C(C=C2)C(F)(F)F)COCC1)C3=NC=C4N=C(N)C(COC5)=C5C4=C3

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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AMG-193 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AMG-193
Cat. No.:
HY-153390
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