VEGF-B
VEGF-B, encoded by the VEGFB gene, is the family member most selective in receptor usage: it binds VEGFR1 and neuropilin-1 but not VEGFR2, and shows far weaker angiogenic activity than VEGF-A. It is expressed predominantly in heart, skeletal muscle, and brain, tissues with high oxidative demand. Acting through VEGFR1 on endothelium, VEGF-B regulates trans-endothelial fatty-acid transport by controlling FATP expression, thereby feeding cardiomyocyte and skeletal-muscle metabolism, and it also supports endothelial and neuronal survival. Recombinant VEGF-B is used in cardiac-protection research, VEGFR1-specific binding assays, and metabolic studies of the vascular-endothelial interface.
-
VEGF-B Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
