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  4. C-Reactive Protein, Mouse (206a.a, HEK293, His)

C-Reactive Protein, Mouse (206a.a, HEK293, His)

Cat. No.: HY-P77908
Handling Instructions

C-Reactive Protein, a liver-produced acute-phase protein, serves as a diagnostic marker for inflammation in diseases. Its clinical significance in disease management and role in inflammation detection make it an important subject of medical research. C-Reactive Protein, Mouse (206a.a, HEK293, His) is the recombinant mouse-derived C-Reactive protein, expressed by HEK293 , with C-His labeled tag. The total length of C-Reactive Protein, Mouse (206a.a, HEK293, His) is 206 a.a., with molecular weight of 26-28 kDa.

For research use only. We do not sell to patients.

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This product has been "discontinued". Optimized version of product available: HY-P74220

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Description

C-Reactive Protein, a liver-produced acute-phase protein, serves as a diagnostic marker for inflammation in diseases. Its clinical significance in disease management and role in inflammation detection make it an important subject of medical research. C-Reactive Protein, Mouse (206a.a, HEK293, His) is the recombinant mouse-derived C-Reactive protein, expressed by HEK293 , with C-His labeled tag. The total length of C-Reactive Protein, Mouse (206a.a, HEK293, His) is 206 a.a., with molecular weight of 26-28 kDa.
Background

C-Reactive Protein (CRP) serves multiple functions crucial for host defense. It facilitates agglutination, bacterial capsular swelling, phagocytosis, and complement fixation by engaging in calcium-dependent interactions with phosphorylcholine. Additionally, CRP exhibits the ability to interact with DNA and histones, suggesting a potential role in scavenging nuclear material released from damaged circulating cells. These diverse functions underscore the versatile and integral role of CRP in the immune response and host defense mechanisms.
Species

Mouse
Source

HEK293
Tag

C-His
Accession

P14847 (H20-S225)
Gene ID

12944  [NCBI]
Molecular Construction
N-term
C-Reactive (H20-S225)
Accession # P14847
His
C-term
Synonyms
C-reactive protein; CRP; PTX1; MGC88244; pentraxin 1; PTX1MGC149895
AA Sequence

HEDMFKKAFVFPKESDTSYVSLEAESKKPLNTFTVCLHFYTALSTVRSFSVFSYATKKNSNDILIFWNKDKQYTFGVGGAEVRFMVSEIPEAPTHICASWESATGIVEFWIDGKPKVRKSLHKGYTVGPDASIILGQEQDSYGGDFDAKQSLVGDIGDVNMWDFVLSPEQISTVYVGGTLSPNVLNWRALNYKAQGDVFIKPQLWS

Molecular Weight

26-28 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

C-Reactive Protein, Mouse (206a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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