PR Protein, Human

PR protein is the B regulatory subunit of PP2A, which regulates substrate selectivity, catalytic activity and directs enzyme localization. PP2A is a phosphatase complex consisting of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). PR Protein, Human is the recombinant human-derived PR protein, expressed by E. coli , with tag free. The total length of PR Protein, Human is 285 a.a., .

The PR protein, as the B regulatory subunit of PP2A, is implicated in modulating substrate selectivity, catalytic activity, and directing the localization of the catalytic enzyme to specific subcellular compartments. PP2A, a phosphatase complex, consists of a core enzyme with a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). This core dimer associates with various regulatory subunits, including the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59, R5/B'/B56 families, the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. The interplay between the PR protein and other regulatory subunits underscores its multifaceted role in shaping the substrate specificity, catalytic function, and subcellular localization of the PP2A enzyme, contributing to its diverse cellular functions.

Human

E. coli

Tag Free

Q06190 (M786-F1070)

5523

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.