RBP7 Protein, Human (His)
Based on 1 Customer Validation
RBP7 protein, a member of the CRBP family, is involved in the stability and metabolism of vitamin A. It binds to all-trans-retinol but with lower affinity compared to other CRBPs. RBP7 protein is expressed in fat, spleen, and other tissues, indicating possible tissue-specific functions. RBP7 Protein, Human (His) is the recombinant human-derived RBP7 protein, expressed by E. coli , with N-6*His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
RBP7 protein, a member of the CRBP family, is involved in the stability and metabolism of vitamin A. It binds to all-trans-retinol but with lower affinity compared to other CRBPs. RBP7 protein is expressed in fat, spleen, and other tissues, indicating possible tissue-specific functions. RBP7 Protein, Human (His) is the recombinant human-derived RBP7 protein, expressed by E. coli , with N-6*His labeled tag.
The RBP7 protein, belonging to the cellular retinol-binding protein (CRBP) family, plays a crucial role in the stability and metabolism of vitamin A. It exhibits a binding affinity for all-trans-retinol and shares structural similarities with other CRBPs, although its binding affinity for retinol is comparatively lower. Besides its general functions, this protein shows biased expression in fat (RPKM 138.2), spleen (RPKM 25.4), and seven other tissues, suggesting potential tissue-specific roles.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
Q96R05/NP_443192.1 (P2-A134)
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Molecular Construction
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N-term
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6*His
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RBP7 (P2-A134)
Accession # Q96R05/NP_443192.1 -
C-term
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Protein Length
Partial
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Synonyms
RBP7; Retinoid-Binding Protein 7; Retinol Binding Protein 7; CRABP4; CRBPIV; CRBP4; Cellular Retinoic Acid-Binding Protein IV; Putative Cellular Retinol-Binding Protein CRBP IV; Cellular Retinoic Acid-Binding Protein 4; RBP7 Protein; Retinol Binding Prote
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AA Sequence
PADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEMFCEGQVCKQTFQRA
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Predicted Molecular Mass
16 kDa
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Molecular Weight
Approximately 16 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, 300 mM NaCl, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (235 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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