RBP7 - retinol binding protein 7 Gene

Also Known as CRBP4; CRABP4; CRBPIV

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116362

About RBP7

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:9,997,228-10,016,021 (from NCBI)

This gene has 2 transcripts (splice variants), 185 orthologues and 15 paralogues. Biased expression in fat (RPKM 138.2), spleen (RPKM 25.4) and 7 other tissues.

Summary

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to Other CRBPs; however, it has a lower binding affinity for retinol than Other CRBPs. [provided by RefSeq, Aug 2016]

RBP7 Products (1)

mRNA Protein Name
NM_052960.3 NP_443192.1 retinoid-binding protein 7

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25814554 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBP7 Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (6 - 133)

  • 0
  • 100
  • 134 a.a.
Protein Preferred Names Protein Names

retinoid-binding protein 7

  • cellular retinoic acid-binding protein 4

RBP7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RBP7 Q96R05 NCKIPSD Homo sapiens Q9NZQ3-3
Y2H Prey Pooling
32296183
Intra
RBP7 Q96R05 NCKIPSD Homo sapiens Q9NZQ3-3
Validated Y2H
32296183
Intra
RBP7 Q96R05 NCKIPSD Homo sapiens Q9NZQ3-3
Y2H Array
32296183
Intra
RBP7 Q96R05 SOCS4 Homo sapiens Q8WXH5
Validated Y2H
25814554
Intra
RBP7 Q96R05 PIK3R3 Homo sapiens Q92569
Validated Y2H
25814554
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant RBP7 Proteins

Cat. No. Product Name Accession Purity
HY-P71251A RBP7 Protein, Human (His) Q96R05/NP_443192.1 (P2-A134) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11771 RBP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19374 Rbp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21912 Polr2g Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25866 Rbp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RBP7 RGD RGD:1562168
Mus musculus RBP7 MGD MGI:1890409
Felis catus RBP7 VGNC VGNC:64538
Bos taurus RBP7 VGNC VGNC:33817
Canis familiaris RBP7 VGNC VGNC:53436
Others RBP7 NCBI