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STC2/Stanniocalcin-2 Protein, Mouse

Cat. No.: HY-P71450
COA Handling Instructions

The STC2/Stanniocalcin-2 protein exerts anti-hypocalcemia effects and is actively involved in the regulation of calcium and phosphate homeostasis. Its role in maintaining the balance of these essential minerals emphasizes its importance in physiological processes related to mineral metabolism. STC2/Stanniocalcin-2 Protein, Mouse is the recombinant mouse-derived STC2/Stanniocalcin-2 protein, expressed by E. coli , with tag free. The total length of STC2/Stanniocalcin-2 Protein, Mouse is 272 a.a., with molecular weight of ~34 kDa.

For research use only. We do not sell to patients.

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Description

The STC2/Stanniocalcin-2 protein exerts anti-hypocalcemia effects and is actively involved in the regulation of calcium and phosphate homeostasis. Its role in maintaining the balance of these essential minerals emphasizes its importance in physiological processes related to mineral metabolism. STC2/Stanniocalcin-2 Protein, Mouse is the recombinant mouse-derived STC2/Stanniocalcin-2 protein, expressed by E. coli , with tag free. The total length of STC2/Stanniocalcin-2 Protein, Mouse is 272 a.a., with molecular weight of ~34 kDa.

Background

Stanniocalcin-2 (STC2) is a protein with an anti-hypocalcemic action, actively participating in the regulation of calcium and phosphate homeostasis. STC2 forms homodimers through disulfide linkages, emphasizing its structural organization. Its anti-hypocalcemic activity suggests a crucial role in maintaining appropriate levels of calcium and phosphate in the body, highlighting its potential significance in various physiological processes. Further research may delve into the specific molecular pathways through which STC2 modulates calcium and phosphate homeostasis, shedding light on its broader implications for overall systemic balance and its potential relevance in therapeutic contexts related to mineral metabolism.

Species

Mouse

Source

E. coli

Tag

Tag Free

Accession

O88452 (25T-296R)

Gene ID

20856  [NCBI]

Molecular Construction
N-term
STC2 (25T-296R)
Accession # O88452
C-term
Synonyms
Stc2; Stanniocalcin-2; STC-2
AA Sequence

TDSTNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVFQLQRECYLKHDLCSAAQENVGVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVKEAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPHHRDTDHHLTANRGAKGERGSKSHPNAHARGRTGGQSAQGPSGSSEWEDEQSEYSDIRR

Molecular Weight

Approximately 34 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against solution in Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

STC2/Stanniocalcin-2 Protein, Mouse Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
STC2/Stanniocalcin-2 Protein, Mouse
Cat. No.:
HY-P71450
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