Synaptotagmin VI Protein, Human (His)

The Ptk7 protein is a receptor involved in multiple cellular processes, including cell proliferation and migration. It plays a crucial role in regulating embryonic development and tissue homeostasis. Synaptotagmin VI Protein, Human (His) is the recombinant human-derived Synaptotagmin VI protein, expressed by E. coli , with N-His labeled tag. The total length of Synaptotagmin VI Protein, Human (His) is 152 a.a., with molecular weight of ~20 kDa.

Synaptotagmin VI protein, a member of the synaptotagmin family, possesses a common domain structure comprising a transmembrane domain and a cytoplasmic region consisting of 2 C2 domains. These proteins play a vital role in calcium-dependent exocytosis of synaptic vesicles. Specifically, synaptotagmin VI is a crucial component of the secretory machinery involved in acrosomal exocytosis. This gene exhibits alternatively spliced transcript variants. Furthermore, it demonstrates biased expression in specific tissues, including the brain (RPKM 2.6), kidney (RPKM 0.8), and 6 other tissues.

Human

E. coli

N-His

NP_995320 (V359-L510)

148281  [NCBI]

Approximately 20 kDa

Greater than 85% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.