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tnfrsf1a-human-his

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P700505
    DR6/TNFRSF21 Protein, Human (His-SUMO)

    Death receptor 6; CD358

    		 Human E. coli
    DR6/TNFRSF21 Protein, central to apoptosis, activates NF-kappa-B, BAX-mediated apoptosis, and mitochondrial cytochrome c release. In neuronal apoptosis, it's pivotal for amyloid peptide-triggered cell body death and axonal pruning. It negatively regulates oligodendrocyte survival, maturation, and myelination. In T-cell signaling, it's crucial for differentiation, proliferation, and immune response, inhibiting T-cell cytokine release and Ig production. Additionally, it regulates pyroptosis by recruiting CASP8 upon ROS stimulation. Interactions include NGFR, CASP8, N-APP, and association with TRADD. DR6/TNFRSF21 Protein, Human (His-SUMO) is the recombinant human-derived DR6/TNFRSF21 protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of DR6/TNFRSF21 Protein, Human (His-SUMO) is 285 a.a., with molecular weight of 48 kDa.

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