1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. SCH 50911 hydrochloride

SCH 50911 hydrochloride 

Cat. No.: HY-12783
Handling Instructions

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

For research use only. We do not sell to patients.

SCH 50911 hydrochloride Chemical Structure

SCH 50911 hydrochloride Chemical Structure

CAS No. : 160415-07-6

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Description

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

IC50 & Target

GABA(B)

1.1 μM (IC50)

Molecular Weight

209.67

Formula

C₈H₁₆ClNO₃

CAS No.

160415-07-6

SMILES

O=C(O)C[[email protected]]1CNC(C)(C)CO1.[H]Cl

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
SCH 50911 hydrochloride
Cat. No.:
HY-12783
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