1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. SCH 50911 hydrochloride

SCH 50911 hydrochloride 

Cat. No.: HY-12783
Handling Instructions

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

For research use only. We do not sell to patients.

SCH 50911 hydrochloride Chemical Structure

SCH 50911 hydrochloride Chemical Structure

CAS No. : 160415-07-6

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Description

SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.

IC50 & Target

GABA(B)

1.1 μM (IC50)

Molecular Weight

209.67

Formula

C8H16ClNO3

CAS No.
SMILES

O=C(O)C[C@H]1CNC(C)(C)CO1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SCH 50911 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SCH 50911 hydrochloride
Cat. No.:
HY-12783
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