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Results for "1135210-68-2" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-B1803A
    Tracazolate hydrochloride

    ICI 136753 hydrochloride

    GABA Receptor Neurological Disease
    Tracazolate hydrochloride (ICI 136753 hydrochloride) is a potent GABAA receptor modulator. Tracazolate hydrochloride potentiates α1β1γ2s (EC50=13.2 μM) and α1β3γ2 (EC50=1.5 μM) in a concentration-dependent manner. Tracazolate hydrochloride has the potency (EC50) is determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity.