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Targets Recommended: PI4K MAP4K Oct3/4 FXR Serotonin Transporter

Results for "1644443-92-4" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-115570
    GW406108X

    GW108X

    Kinesin ULK Autophagy Cancer
    GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signalling kinases mTORC1 and AMPK.