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Cat. No. Product Name Target Research Areas
  • HY-120035

    Proteasome Ribosomal S6 Kinase (RSK) Cancer
    DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation.