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2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W392836

    Nucleoside Antimetabolite/Analog Cancer
    2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia .
    2'-O-<em>Methyl</em>-5'-O-<em>dmt</em>-<em>inosine</em>-3'-CE-<em>phosphoramidite</em>

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