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Results for "2041073-22-5" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-129492
    GNF4877

    DYRK GSK-3 Metabolic Disease
    GNF4877 is a potent inhibitor of DYRK1A and GSK3β with IC50s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (EC50 of 0.66 μM for mouse β (R7T1) cells).