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Results for "2230757-47-6" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-135334

    Drug Metabolite Btk Cancer
    ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM.