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Targets Recommended: CRISPR/Cas9 p38 MAPK

Results for "2245887-38-9" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-124602
    DI-591

    E1/E2/E3 Enzyme Cancer
    DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591 selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members.