1. Search Result

Search Result

Targets Recommended: NEDD8-activating Enzyme

Results for "371980-94-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Areas
  • HY-18617
    SB-612111 hydrochloride

    Opioid Receptor Inflammation/Immunology Neurological Disease
    SB-612111 hydrochloride is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 hydrochloride exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model.