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Targets Recommended: NEDD8-activating Enzyme

Results for "522649-59-8" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-124861
    Malic enzyme inhibitor ME1


    Apoptosis Cancer Metabolic Disease
    Malic enzyme inhibitor ME1 (ME1) is a multifunctional protein involved in glycolysis, the citric acid cycle, NADPH production, glutamine metabolism, and lipogenesis. Malic enzyme inhibitor ME1 regulates one of the main pathways that provide nicotinamide adenine dinucleotide phosphate (NADPH), which is essential for cancer cell growth through maintenance of redox balance and biosynthesis processes in the cytoplasm. Malic enzyme inhibitor ME1 disrupts metabolism in cancer cells and inhibits cancer cell growth by inducing senescence or apoptosis .