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Targets Recommended: CRISPR/Cas9

Results for "642008-81-9" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-122586
    BRD6989

    CDK Interleukin Related Inflammation/Immunology
    BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes.