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" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P700396
    ANGPT2/Angiopoietin-2, Dog (HEK293, His)

    ANGiopoietin 2; ANGiopoietin-2; ANG2; ANG-2; Tie2-ligand; ANGiopoietin-2B; ANGiopoietin-2a; ANG2; AGPT2

    		 Dog HEK293
    ANGPT2/Angiopoietin-2, Dog, intricately modulates angiogenesis by binding to TEK/TIE2, competitively impacting ANGPT1 signaling. It induces TEK/TIE2 phosphorylation independently and, in the absence of VEGF, may lead to endothelial apoptosis, contributing to vascular regression. Collaborating with VEGF, ANGPT2 facilitates angiogenesis, promoting endothelial cell migration and proliferation. Additionally, ANGPT2 regulates lymphangiogenesis, emphasizing its comprehensive role in vascular dynamics within dog biology. Its interactions with TEK/TIE2 and ITGA5 highlight its multifaceted contribution to angiogenesis and vascular regulation. ANGPT2/Angiopoietin-2, Dog (HEK293, His) is the recombinant dog-derived ANGPT2/Angiopoietin-2, Dog, expressed by HEK293, with C-6*His labeled tag. The total length of ANGPT2/Angiopoietin-2, Dog (HEK293, His) is 477 a.a., with molecular weight of 57.2 kDa.

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