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Results for "

BMAL1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148765
    CLK8

    		Cryptochrome Metabolic Disease Cancer
    CLK8 is a potent and specific CLOCK inhibitor that can disrupt the interaction between CLOCK and BMAL1 and interfere with nuclear translocation of CLOCK. CLK8 can be used for the research of disorders associated with dampened circadian rhythms [1].
    CLK8
  • HY-148711
    STL1267

    		REV-ERB Metabolic Disease Inflammation/Immunology Cancer
    STL1267 is a potent and cross-the-blood-brain barrier REV-ERB agonist with a Ki value of 0.16 µM for REV-ERBα. STL1267 shows no cytotoxicity. STL1267 inhibits the gene expression of BMAL1 [1].
    STL1267
  • HY-115672
    KS15
    1 Publications Verification

    		 Cryptochrome Cancer
    KS15 is an inhibitor of the interactions between cryptochromes (CRYs: CRY1 and CRY2) and the CLOCK:BMAL1 heterodimer. KS15 impairs the feedback actions of CRYs on E-box-dependent transcription (EC50=4.9 μM) by CLOCK:BMAL1 heterodimer, an indispensable transcriptional regulator of the mammalian circadian clock. Anti-proliferative activity [1] .
    KS15
  • HY-14414
    GSK4112
    5 Publications Verification

    SR6452

    		 REV-ERB Apoptosis Metabolic Disease
    GSK4112 (SR6452) is a Rev-erbα agonist with an EC50 value of 0.4 μM. GSK4112 can be used as a chemical tool to probe the function of Rev-erbα in transcriptional repression, regulation of circadian biology, and metabolic pathways [1].
    GSK4112
  • HY-RS01529
    BMAL1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BMAL1 Human Pre-designed siRNA Set A contains three designed siRNAs for BMAL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BMAL1 Human Pre-designed siRNA Set A
    BMAL1 Human Pre-designed siRNA Set A

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