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CHEK1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P74253
    Chk1 Protein, Mouse (sf9, His-GST)

    Serine/threonine-protein kinase Chk1; CHEK1; Chk1

    		 Mouse Sf9 insect cells
    Chk1 is a serine/threonine protein kinase that critically coordinates checkpoint-mediated cell cycle arrest and DNA repair in response to DNA damage or unreplicated DNA. It negatively regulates unperturbed cell cycle progression and protects genome integrity by phosphorylating key targets such as CDC25A, CDC25B, CDC25C, RAD51, TP53, histone H3.1, RB1, SPRTN, TLK1 and FANCE. Chk1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Chk1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Chk1 Protein, Mouse (sf9, His-GST) is 476 a.a., with molecular weight of ~78 kDa.

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