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Results for "

D04

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115627
    PKUMDL-LC-101-D04
    1 Publications Verification

    GPX4-Activator-1d4

    		 Glutathione Peroxidase Inflammation/Immunology
    PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts .
    PKUMDL-LC-101-<em>D04</em>
  • HY-12847
    CCT241161

    		Raf Src Apoptosis Cancer
    CCT241161 is an orally active pan-RAF inhibitor with IC50s of 3, 6, 10, 15 and 30 nM for LCK, CRAF, SRC, V600E-BRAF and BRAF, respectively. CCT241161 shows good activity to in BRAF and NRAS mutant melanomas. CCT241161 also exhibits anticancer cell proliferative activity .
    CCT241161

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