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FGFR-IN-10

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148597
    FGFR-IN-10

    		FGFR Cytochrome P450 Cancer
    FGFR-IN-10 is an orally active inhibitor of FGFR and Cytochrome P450 (CYPs). FGFR-IN-10 inhibits wide type and V564F mutant FGFR2 with IC50s of 104.1 nM and 43.6 nM, respectively. FGFR-IN-10 also inhibits CYPs with IC50s of 3.33 μM (CYP2C9), 18.75 μM (CYP2C19), 4.34 μM (CYP2CD6), and 0.69 μM (CYP3A4), respectively .
    <em>FGFR-IN-10</em>

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