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Results for "

J1-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155999
    MoTPS1-IN-1

    		Fungal Infection
    MoTPS1-IN-1 (Compound j11), an antifungal agent, is a MoTPS1 inhibitor. MoTPS1-IN-1 acts by interation with Glu396 in MoTPS1. MoTPS1-IN-1 inhibits pathogenicity of M. oryzae .
    MoTPS1-IN-1
  • HY-15648F
    GSK-J4 hydrochloride
    30+ Cited Publications

    		 Histone Demethylase Cancer
    GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-α production in human primary macrophages with an IC50 of 9 μM. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1 .
    GSK-J4 hydrochloride
  • HY-15648B
    GSK-J4
    30+ Cited Publications

    		 Histone Demethylase Apoptosis Cancer
    GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively. GSK-J4 inhibits LPS-induced TNF-α production in human primary macrophages with an IC50 of 9 μM. GSK J4 is a cell permeable proagent of GSK-J1 . GSK-J4 induces endoplasmic reticulum stress-related apoptosis .
    GSK-J4
  • HY-149713
    J1-1

    		ICMT Cancer
    J1-1 is an inhibitor of ICMT with an IC50 of 1.0 μM and has anticancer activity .
    <em>J1-1</em>

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