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JPT1

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P74880
    HN1 Protein, Mouse (His)

    Jupiter microtubule associated homolog 1; JPT1; Hn1

    		 Mouse E. coli
    HN1 protein negatively regulates AKT-mediated GSK3B signaling and induces the phosphorylation and degradation of CTNNB1 at “Ser-33”. This effect inhibits the “Ser-9” phosphorylation of GSK3B, inhibits the activity of APC:CTNNB1:GSK3B complex and blocks its interaction with CDH1. HN1 Protein, Mouse (His) is the recombinant mouse-derived HN1 protein, expressed by E. coli , with N-His labeled tag. The total length of HN1 Protein, Mouse (His) is 154 a.a., with molecular weight of ~18.3 kDa.

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