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NLRP3-IN-20

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156121
    NLRP3-IN-20

    		NOD-like Receptor (NLR) Inflammation/Immunology Cancer
    NLRP3-IN-20 (compound 11) is an orally available inhibitor of the NLRP3 inflammasome with an IC50 of 25 nM for IL-1β secretion. NLRP3-IN-20 has excellent pharmacokinetic properties and demonstrated significant efficacy in models of non-alcoholic steatohepatitis, fatal septic shock, and colitis .
    <em>NLRP3-IN-20</em>

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