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PGD-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108259
    HQL-79

    		PGE synthase Inflammation/Immunology
    HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
    HQL-79
  • HY-110167
    TFC 007

    		PGE synthase Ligands for Target Protein for PROTAC Cancer
    TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon) [1].
    TFC 007
  • HY-113096
    Prostaglandin D1

    PGD1

    		 Endogenous Metabolite Metabolic Disease
    Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research [1] .
    Prostaglandin D<em>1</em>
  • HY-134860
    Prostaglandin D1 alcohol

    		Others Metabolic Disease
    Prostaglandin D1 (PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl [1].
    Prostaglandin D<em>1</em> alcohol

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