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Spicamycin

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-127130
    Spicamycin

    		Bcl-2 Family Apoptosis Fungal Antibiotic Infection Cancer
    Spicamycin, an adenine nucleoside antibiotic with antifungal and antitumor activities. Spicamycin is also a potent inducer of differentiation of myeloid leukemia cells. Spicamycin induces apoptosis in NB4 cells via down-regulation of Bcl-2 expression and modulation of PML protein .
    <em>Spicamycin</em>
  • HY-13659
    KRN5500

    NSC 650426

    		 Antibiotic Bcl-2 Family Apoptosis Infection Cancer
    KRN5500 (NSC 650426), a Spicamycin (HY-127130) derivative and a nucleoside-like antibiotic with anti-tumor activity. KRN5500 also induces apoptosis via the down-regulation of Bcl-2 expression. KRN5500 shows a significant efficacy in the human tumor xenograft model in mice .
    KRN5500

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