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Results for "

TM-2

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121493
    TM2-115

    		Histone Methyltransferase Parasite Infection
    TM2-115 inhibits malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death .
    <em>TM2</em>-115
  • HY-136882
    TM-1

    		PDHK Cancer
    TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation .
    TM-1
  • HY-RS14605
    TM2D3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TM2D3 Human Pre-designed siRNA Set A contains three designed siRNAs for TM2D3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TM2D3 Human Pre-designed siRNA Set A
    TM2D3 Human Pre-designed siRNA Set A
  • HY-163173
    TEAD-IN-8

    		YAP Cancer
    TEAD-IN-8 is a novel TEAD inhibitor, which potently and specifically inhibits TEAD-YAP transcriptional activities. TM2, alone or in combination with MEK inhibitors, exhibits potent antiproliferative effects in YAP-dependent cancer cells .
    TEAD-IN-8
  • HY-143863
    PPARδ agonist 8

    		PPAR Metabolic Disease
    Pparδ agonist 8 is a potent agonist of Pparδ. The peroxisome proliferator-activated receptor (PPAR) is a member of the intranuclear receptor transcription factor superfamily that plays a key role in the regulation of metabolic homeostasis, inflammation, cell growth and differentiation in vivo. Pparδ agonist 8 has the potential for the research of non-alcoholic fatty liver disease (NAFLD) (extracted from patent WO2021169769A1, compound TM2) .
    PPARδ agonist 8

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