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TPE-MI

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-143218
    TPE-MI
    1 Publications Verification

    Tetraphenylethene maleiMIde

    		 Huntingtin Parasite Neurological Disease
    TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
    <em>TPE-MI</em>

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