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TTBK1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134968
    TTBK1-IN-1
    1 Publications Verification

    		 Tau Protein Neurological Disease
    TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimer’s disease and related tauopathies [1]. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    <em>TTBK1</em>-IN-<em>1</em>
  • HY-145313
    TTBK1-IN-2

    		Others Neurological Disease
    TTBK1-IN-2 (compound 29) is a potent Tau-Tubulin kinase (TTBK1) inhibitor with IC50s of 0.24 and 4.22 µM, respectively. TTBK1-IN-2 reveals good brain penetration in vivo and is able to reduce TDP-43 phosphorylation not only in cell cultures but also in the spinal cord of transgenic TDP-43 mice [1].
    <em>TTBK1</em>-IN-2
  • HY-134968A
    (R)-TTBK1-IN-1

    		Tau Protein Neurological Disease
    (R)-TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor. (R)-TTBK1-IN-1 is an enantiomer of TTBK1-IN-1 (HY-134968). (R)-TTBK1-IN-1 can be used in the research of alzheimer’s disease and related tauopathies [1]. (R)-TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (R)-<em>TTBK1</em>-IN-<em>1</em>
  • HY-RS15193
    TTBK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TTBK1 Human Pre-designed siRNA Set A contains three designed siRNAs for TTBK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TTBK1 Human Pre-designed siRNA Set A
    TTBK1 Human Pre-designed siRNA Set A

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