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VCL

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P73549
    Vinculin Protein, Mouse (HEK293, His)

    Vinculin; Metavinculin; VCL

    		 Mouse HEK293
    Vinculin Protein, a crucial actin filament (F-actin)-binding protein, actively engages in cell-matrix and cell-cell adhesion, regulating E-cadherin expression and enhancing mechanosensing with the E-cadherin complex for cell morphology and locomotion (By similarity). Vinculin self-associates and is part of a complex with THSD1, PTK2/FAK1, TLN1, and VCL (By similarity). Interactions with proteins like APBB1IP, NRAP, TLN1, SYNM, CTNNB1, SORBS1, and CTNNA1 serve specific cellular functions. The CTNNB1 interaction is crucial for vinculin's localization to cell-cell junctions and its role in regulating E-cadherin surface expression (By similarity). Additionally, vinculin binds to ACTN4, inducing conformational changes for functional versatility (By similarity). Vinculin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Vinculin protein, expressed by HEK293, with C-His labeled tag. The total length of Vinculin Protein, Mouse (HEK293, His) is 1066 a.a., with molecular weight of ~118 kDa.

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