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hAChE/hBACE-1-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149288
    hAChE/hBACE-1-IN-2

    		Cholinesterase (ChE) Beta-secretase Amyloid-β
    hAChE/hBACE-1-IN-2 is a potent, orally active, blood-brain barrier transboundary triple inhibitor of hAChE, hBChE, and HACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM, respectively. hAChE/hBACE-1-IN-2 has antioxidant activity. hAChE/hBACE-1-IN-2 also inhibits Aβ11-42 aggregation. hAChE/hBACE-1-IN-2 can be used to study Alzheimer's disease .
    <em>hAChE/hBACE-1-IN-2</em>

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