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By Targets:	Endogenous Metabolite (1) HIV (1) Ser/Thr Protease (1) Toll-like Receptor (TLR) (2) VD/VDR (1)
By Research Areas:	Cardiovascular Disease (2) Inflammation/Immunology (3) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-75958

Vitamin D4 1 Publications Verification 22-Dihydroergocalciferol	VD/VDR	Metabolic Disease
Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol .

HY-E70110

Endo-1,4-β-mannanase	Others	Others
Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose .

HY-143222

AS(3n-1)-Inclisiran

Others Others

AS(3n-1)-Inclisiran is the antisense of inclisiran with 3N random site after the 1 bp spacer[1].

AS(3n-1)-Inclisiran	Others	Others
AS(3n-1)-Inclisiran is the antisense of inclisiran with 3N random site after the 1 bp spacer[1].

HY-143223

AS(3n-2)-Inclisiran	Ser/Thr Protease	Others
AS(3n-2)-Inclisiran is the antisense of Inclisiran with 3 N random site after the 2 bp spacer. Inclisiran is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9 .

HY-P4114

TAT-NSF700scr	HIV	Others
TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite	Others
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

HY-153840

ODN INH 18	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN INH-18 is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 showes inhibitory potency for TLR9 ligand-induced IFN-α production.

HY-153840A

ODN INH 18 sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN INH-18 sodium is a linear 24-mer class B INH-ODN in which the 5' INH-ODN 4084-F sequence was followed by a random stretch of 12 nucleotides lacking the ability to form significant secondary structures. ODN INH-18 sodium showes inhibitory potency for TLR9 ligand-induced IFN-α production.

Cat. No.	Product Name

HY-L901

50K Diversity Library	50000 compounds
MCE 50K Diversity Library consists of 50,000 lead-like compounds with multiple characteristics such as calculated good solubility (-3.2<logP<5), oral bioavailability (RotB<=10), drug transportability (PSA<120). These compounds were selected by dissimilarity search with an average Tanimoto Coefficient of 0.52. There are 36,857 unique scaffolds and each scaffold 1 to 7 compounds. What’s more, compounds with the same scaffold have as many functional groups as possible, which make abundant chemical spaces. This exceptionally diverse library is highly recommended for random screening against new as well as popular targets based its novel, diverse scaffolds, abundant chemical spaces and the convenience for subsequent modification.

50K Diversity Library

50000 compounds

MCE 50K Diversity Library consists of 50,000 lead-like compounds with multiple characteristics such as calculated good solubility (-3.2<logP<5), oral bioavailability (RotB<=10), drug transportability (PSA<120). These compounds were selected by dissimilarity search with an average Tanimoto Coefficient of 0.52. There are 36,857 unique scaffolds and each scaffold 1 to 7 compounds. What’s more, compounds with the same scaffold have as many functional groups as possible, which make abundant chemical spaces. This exceptionally diverse library is highly recommended for random screening against new as well as popular targets based its novel, diverse scaffolds, abundant chemical spaces and the convenience for subsequent modification.

Cat. No.	Product Name	Type

HY-P3004

Endo-1,3-β-glucanase Lyticase	Biochemical Assay Reagents
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

HY-E70011

Levanase	Biochemical Assay Reagents
Levanase is a slime-dissolving enzyme of Rhodotorula species. Levanase performs random hydrolysis of β-2,6 fructofuranosyl linkages in β-2,6 fructans containing more than 3 fructose units .

Cat. No.	Product Name	Target	Research Area

HY-P1849A

JAG-1, scrambled TFA scJag-1 TFA	Peptides	Cardiovascular Disease
JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control .

HY-P3211B

Nangibotide scrambled peptide LR12-scr	Peptides	Inflammation/Immunology
Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide; HY-P3211) but in a random sequence (YQDVELCETGED) .

HY-P1849

JAG-1, scrambled scJag-1	Peptides	Cardiovascular Disease
JAG-1, scrambled (scJag-1) is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled is usually used as a negative control .

HY-P2517

Scrambled TRAP Fragment	Peptides	Others
Scrambled TRAP Fragment is a scrambled sequence of TRAP Fragment. Scrambled TRAP Fragment with a random sequence of the amino acids that are the same as the active fragment. Scrambled TRAP Fragment usually used as a negative control.

HY-P4114

TAT-NSF700scr	HIV	Others
TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .

HY-P4749

Prion Protein (106-126) (human) (scrambled)	Peptides	Neurological Disease
Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of Prion Protein (106-126). Prion Protein (106-126) (human) (scrambled) with a random sequence of the amino acids that are the same as the active fragment. Prion Protein (106-126) (human) (scrambled) usually used as a negative control .

HY-P3004

Endo-1,3-β-glucanase Lyticase	Endogenous Metabolite	Others
Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies .

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