JAG-1, scrambled TFA
Based on 2 publication(s) in Google Scholar
JAG-1, scrambled (scJag-1) TFA is a scrambled sequence of JAG-1 (Jagged-1 protein). JAG-1, scrambled TFA has a random sequence of the amino acids that are the same as the active fragment. JAG-1, scrambled TFA is usually used as a negative control.
For research use only. We do not sell to patients.
- Purity: 99.75%
- Formula: C95H128F3N25O28S3
- Molecular Weight:2221.37
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) JAG-1, scrambled TFA
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Biological Activity
In contrast to JAG-1, pretreatment of human pulmonary arterial smooth muscle cells (PASMC) with 50 μM scJag-1 TFA for 30 min has no effect on the transient and plateau components of store-operated Ca2+ entry (SOCE) in comparison to the cells treated with vehicle used to dissolve scJag-1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2221.37
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Formula C95H128F3N25O28S3
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Color White to off-white
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Synonyms
scJag-1 TFA
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Sequence Shortening
RCGPDCFDNYGRYKYCF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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Br J Pharmacol
Cordycepin alleviates ischaemic brain injury by suppressing microglia-induced neuroinflammation via regulating the Notch1 signalling pathway. [Abstract]2026 Jul;183(13):3578-3598. PMID: 41913462 -
JCI Insight
CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway. [Abstract]2025 May 8;10(9):e187836. PMID: 40337864
Solvent & Solubility
DMSO : 100 mg/mL (45.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 10 mg/mL (4.50 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 0.4502 mL | 2.2509 mL | 4.5017 mL | 11.2543 mL |
| DMSO | 5 mM | 0.0900 mL | 0.4502 mL | 0.9003 mL | 2.2509 mL |
| 10 mM | 0.0450 mL | 0.2251 mL | 0.4502 mL | 1.1254 mL | |
| 15 mM | 0.0300 mL | 0.1501 mL | 0.3001 mL | 0.7503 mL | |
| 20 mM | 0.0225 mL | 0.1125 mL | 0.2251 mL | 0.5627 mL | |
| 25 mM | 0.0180 mL | 0.0900 mL | 0.1801 mL | 0.4502 mL | |
| 30 mM | 0.0150 mL | 0.0750 mL | 0.1501 mL | 0.3751 mL | |
| 40 mM | 0.0113 mL | 0.0563 mL | 0.1125 mL | 0.2814 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
JAG-1, scrambled TFA Related Classifications
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