2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. α-Conotoxin S IA

α-Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR) antagonist with high affinity for the muscle nAChR. α-Conotoxin SIA preferentially targets the α/δ interface of the muscle nAChR in mouse muscle. In contrast, for Torpedo nAChR, α-Conotoxin SIA has a much higher affinity for the α/γ than for the α/δ interface.

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α-Conotoxin S IA Chemical Structure

α-Conotoxin S IA Chemical Structure

CAS No. : 135190-31-7

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α-Conotoxin S IA Related Antibodies

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Description

α-Conotoxin SIA is a selective nicotinic acetylcholine receptor (nAChR) antagonist with high affinity for the muscle nAChR. α-Conotoxin SIA preferentially targets the α/δ interface of the muscle nAChR in mouse muscle. In contrast, for Torpedo nAChR, α-Conotoxin SIA has a much higher affinity for the α/γ than for the α/δ interface[1].

Molecular Weight

1455.66

Formula

C60H82N18O17S4
CAS No.
Sequence Shortening

YCCHPACGKNFDC-NH2 (Disulfide bridge:Cys2-Cys7;Cys3-Cys13)
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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α-Conotoxin S IA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Conotoxin S IA135190-31-7nAChRNicotinic acetylcholine receptorsmuscleα/δ interfaceα/γ interfaceTorpedo nAChRInhibitorinhibitorinhibit

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